Regulation of Integrin Surface Expression
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United States of America Patent
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app pub date -
Mar 7, 2011
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Aug 20, 2008
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Abstract
Disclosed are methods and compositions for preventing and treating conditions associated with platelet aggregation, comprising administering a therapeutically effective amount of a composition that modifies the interaction of DNAJC10 with αIIbβ3 in a megakaryocyte, thereby altering the expression of αIIbβ3 on the surface of the megakaryocyte.
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