METHODS FOR TREATMENT AND PREVENTION OF OTOTOXICITY BY siRNA
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United States of America Patent
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Issued Date -
Jun 30, 2011
app pub date -
Aug 13, 2007
filing date -
Aug 13, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to methods for reducing and/or preventing ototoxicity caused by an ototoxic agent, noise or head and/or neck radiation. It is also directed to a method for preventing or reducing generation of reactive oxygen species in the inner ear of a patient. The methods of the present invention include administering at least one siRNA directed against TRPV1 mRNA, NOX3 mRNA or a combination thereof.
First Claim
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| Country | kind | publication No. | Filing Date |
|---|---|---|---|
| WO | A1 | WO2009023025 | Aug 13, 2007 |
International Classification(s)
- 2007 Application Filing Year
- A61K Class
- 9805 Applications Filed
- 5595 Patents Issued To-Date
- 57.07 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 1 Citation Count
- A61K Class
- 10.68 % this patent is cited more than
- 14 Age