LYMPHANGIOGENESIS-PROMOTING AGENTS

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United States of America Patent

APP PUB NO 20110160132A1
SERIAL NO

11996898

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Abstract

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Described herein is the discovery that HGFs activate the growth and migration of lymphatic endothelial cells and thereby promote lymphangiogenesis. The present invention is based on this finding, and provides lymphangiogenesis-promoting agents comprising as active ingredients HGFs, or proteins or compounds functionally equivalent thereto. Based on the finding described above, the present invention also provides methods for promoting lymphangiogenesis which comprise the step of locally administering HGFs or proteins functionally equivalent thereto to affected areas in patients with lymphedema.

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Patent Owner(s)

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ANGES MG INCIBARAKI-SHI OSAKA 567-0085

International Classification(s)

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  • 2006 Application Filing Year
  • A61K Class
  • 9598 Applications Filed
  • 4848 Patents Issued To-Date
  • 50.52 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2006200720082009201020112012201320142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kaneda, Yasufumi Osaka, JP 67 530
Morishita, Ryuichi Osaka, JP 102 524
Nakagami, Hironori Osaka, JP 34 76
Saito, Yukihiro Hokkaido, JP 53 417

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7424023113748323813073422412123001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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