METHOD OF DIAGNOSING NEOPLASMS

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United States of America Patent

SERIAL NO

12739559

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Abstract

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The present invention relates generally to a nucleic acid molecule, the RNA and protein expression profiles of which are indicative of the onset, predisposition to the onset and/or progression of a large intestine neoplasm. More particularly, the present invention is directed to a nucleic acid molecule, the expression profiles of which are indicative of the onset and/or progression of a colorectal neoplasm, such as an adenoma or an adenocarcinoma. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenomas and adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening a subject for the onset, predisposition to the onset and/or progression of a large intestine neoplasm by screening for modulation in the expression profile of said nucleic acid molecule markers.

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Patent Owner(s)

Patent OwnerAddress
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATIONCAMPBELL ACT 2601
CLINICAL GENOMICS PTY LTDNORTH RYDE NEW SOUTH WALES 2113

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Glenn Southwell New South Wales, AU 2 3
Dunne, Robert New South Wales, AU 15 31
Graham, Lloyd Douglas New South Wales, AU 4 3
Lapointe, Lawrence Charles New South Wales, AU 13 22
Molloy, Peter New South Wales, AU 18 50
Pedersen, Susanne New South Wales, AU 10 18
Young, Graéme P South Australia, AU 1 3

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