TARGETED BLOCK COPOLYMER MICELLES

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United States of America Patent

APP PUB NO 20110158906A1
SERIAL NO

12673472

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a micelle comprising an amphiphilic block copolymer, said amphiphilic block copolymer consisting of (a) a hydrophobic polymer attached to the 5′ end of a first nucleic acid molecule, wherein said first nucleic acid molecule is hybridized with a second nucleic acid molecule, wherein a targeting unit capable of selectively binding to a specific cell type and/or tissue is attached to the 5′ end of said second nucleic acid molecule; and/or (b) a hydrophobic polymer attached to the 3′ end of a first nucleic acid molecule, wherein said first nucleic acid molecule is hybridized with a second nucleic acid molecule, wherein a targeting unit capable of selectively binding to a specific cell type and/or tissue is attached to the 3′ end of said second nucleic acid molecule.

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Patent Owner(s)

Patent OwnerAddress
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E VHOFGARTENSTRASSE 8 MUNCHEN 80539

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alemdaroglu, Fikri E Mainz, DE 1 5
Alemdaroglu, N Ceren Mainz, DE 1 5
Herrmann, Andreas AG Groningen, DE 209 851
Langguth, Peter Biebergemund, DE 14 110
Müllen, Klaus Koln, DE 18 176

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