MICRONEEDLE ARRAY USING POROUS SUBSTRATE AND PRODUCTION METHOD THEREOF
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United States of America Patent
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Issued Date -
Jun 23, 2011
app pub date -
Mar 2, 2010
filing date -
Jun 3, 2009
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Abandoned
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Abstract
In order to produce a microneedle array which includes a macromolecular drug such as a vaccine antigen and insulin at its acral portion using a water-soluble thread-forming polymer for a base, there is a need for a substrate which enables a solvent to be efficiently removed so that a base dense solution containing a target substance can be dried and cured while still inserted in a mold. This problem is resolved by using a porous water-insoluble substrate or a porous filter as a substrate, which allows drying and curing as well as peeling from a female mold to be carried out while the base dense solution containing a target substance is still filled in the mold.
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