METHOD FOR THE ANALYSIS OF O-LINKED OLIOSACHARIDES
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United States of America Patent
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Issued Date -
Jun 16, 2011
app pub date -
Aug 11, 2009
filing date -
Aug 19, 2008
priority date (Note) -
Abandoned
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Abstract
A method of analyzing O-linked oligosaccharides in a sample is disclosed. The method comprises the steps of digesting a glycoprotein with a proteolytic enzyme, performing solid-phase permethylation of the oligosaccharide, then analyzing the permethylated and non-reduced O-linked oligosaccharides using MALDI-TOF mass spectrometry.
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