METHOD FOR THE ANALYSIS OF OLIGONUCLEOTIDES
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United States of America Patent
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Issued Date -
Jun 9, 2011
app pub date -
Aug 7, 2009
filing date -
Aug 20, 2008
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Abandoned
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Abstract
A method for the analysis of oligonucleotides is provided. The method comprises: desalting a mixture of oligonucleotides under conditions such that there is substantially no separation of the mixture of oligonucleotides, and/or by on-line desalting, introducing the desalted mixture of oligonucleotides into a mass spectrometer; and quantifying one or more oligonucleotides comprised in the mixture by mass spectrometry.
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