SYNTHETIC AGONISTS OF TLR9
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United States of America Patent
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app pub date -
Dec 3, 2010
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Dec 12, 2006
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Abstract
The invention provides novel oligonucleotide-based compounds that individually provide distinct immune response profiles through their interactions as agonists with TLR9. The TLR9 agonists according to the invention are characterized by specific and unique chemical modifications, which provide their distinctive immune response activation profiles.
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