METHODS FOR TREATING APOLIPOPROTEIN E4-ASSOCIATED DISORDERS
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United States of America Patent
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Dec 1, 2010
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Dec 3, 2009
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Abstract
The present disclosure provides a method of increasing the functionality of a GABAergic interneuron in the hilus of the hippocampus of an individual having at least one apolipoprotein E4 (apoE4) allele. The method generally involves reducing tau levels in the interneuron.
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