METHODS FOR TREATING FATTY LIVER DISEASE
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United States of America Patent
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Issued Date -
Jun 2, 2011
app pub date -
Nov 3, 2010
filing date -
Nov 3, 2009
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Abstract
In certain aspects, the present invention provides compositions and methods for treating fatty liver disease by administering an antagonist of an ActRIIB signaling pathway. Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies and anti-activin A or B antibodies. A variety of hepatic and metabolic disorders may be improved by treating fatty liver disease.
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