LOW-VOLUME SEQUENCING SYSTEM AND METHOD OF USE
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United States of America Patent
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Issued Date -
May 26, 2011
app pub date -
Aug 31, 2010
filing date -
Aug 31, 2009
priority date (Note) -
Abandoned
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Abstract
Various embodiments of a low-volume sequencing system are provided herein. The system can include a low-volume flowcell having at least one reaction chamber of a defined volume (e.g., less than about 100 μl). The system can also include an automated reagent delivery mechanism configured to reversibly couple with the inlet port corresponding to a target reaction chamber thereby placing allowing for reagent to be accurately moved from a storage container to the reaction chamber with minimal reagent waste. The flowcells can include a plurality of reaction chambers (e.g., 6) thereby allowing for parallel analysis of multiple samples. Various methods of analyzing a biomolecule are also provided herein.
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