METHOD OF RATIONAL-BASED DRUG DESIGN USING OSTEOCALCIN
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United States of America Patent
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app pub date -
Feb 1, 2011
filing date -
Oct 23, 2003
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Abstract
The invention relates to a method of identifying a compound that affects osteocalcin activity, comprising obtaining a 3D structure of osteocalcin or a fragment thereof, designing a compound to interact with, or mimic, the 3D structure of osteocalcin or fragment thereof, obtaining the compound, and determining whether the compound affects osteocalcin activity.
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