Taylor Vortex Flow Bioreactor for Cell Culture
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United States of America Patent
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Issued Date -
May 19, 2011
app pub date -
Jun 5, 2009
filing date -
Jun 5, 2008
priority date (Note) -
Abandoned
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Abstract
The invention concerns a rotating wall vessel bioreactor (100) using Taylor vortex flow for cell culture in the annular space between the two concentric cylindrical bodies, wherein the internal one (2) is rotating and the external one (1) is stationary. The internal rotating body (2) is composed of an external wall around which a polymeric tubular membrane (6) is wrapped, which is connected to the hollow tubular axis (5) of the internal body (2) for the introduction of gases into the annular space (d). Said annular space (d) is filled with a suspension of cells or cells immobilized on microcarriers.
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