Bicyclic androgen and progesterone receptor modulator compounds and methods
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United States of America Patent
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Issued Date -
Mar 18, 2010
app pub date -
Nov 13, 2009
filing date -
Aug 27, 1999
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Abandoned
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Abstract
The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.
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