Bacteriophage/Quantum-Dot (Phage-QD) Nanocomplex to Detect Biological Targets in Clinical and Environmental Isolates

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United States of America Patent

SERIAL NO

11884604

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Abstract

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The invention is related to a non-biotinylated bacteriophage that comprises a nucleic acid sequence encoding a biotinylation domain, a complex that comprises a biotinylated bacteriophage and a biotin-specific ligand conjugated bioconjugate, and a method of detecting a bacterial cell in a sample comprising contacting the sample with a non-biotinylated bacteriophage that comprises a nucleic acid sequence encoding a biotinylation domain, wherein the bacteriophage is specific to the bacterial cell.

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Patent Owner(s)

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GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY100 BUREAU DRIVE MS 2200 GAITHERSBURG MD 20899-2200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adhya, Sankar Gaithersburg, US 6 155
Edgar, Rotem Potomac, US 5 113
Giulian, Gary Gaithersburg, US 2 29
Hwang, Jeeseong Gaithersburg, US 3 23
Mckinstry, Michael Fairmont, US 4 112
Merril, Carl Bethesda, US 10 30

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