METHOD FOR ENZYMATIC CROSS-LINKING OF A PROTEIN
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United States of America Patent
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Issued Date -
Apr 14, 2011
app pub date -
Jun 18, 2009
filing date -
Jun 18, 2008
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Abandoned
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Abstract
A method for cross-linking albumin for use as a sealant or glue for a biological system, for example to induce hemostasis and/or prevent leakage of any other fluid from a biological tube or tissue, such as lymph for example. The cross-linked albumin may optionally and preferably be applied as part of a bandage for example. In other embodiments, the present invention provides a method of enzymatically cross-linking globular proteins, by altering the structure of the protein to improve the accessibility of the protein to the cross-linking enzyme.
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