Selection of B Cells with Specificity of Interest: Method of Preparation and Use
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United States of America Patent
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Oct 5, 2009
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May 15, 2003
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Abstract
The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides methods using a composition comprising an ordered and repetitive antigen or antigenic determinant array for visualization and selection of B cells specific for the antigen. These B cells are useful for the production of monoclonal antibodies used for therapy, diagnostic or research purposes.
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