THERAPEUTIC AGENT FOR LOCAL INFLAMMATION
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United States of America Patent
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Issued Date -
Apr 7, 2011
app pub date -
Jun 23, 2006
filing date -
Jun 28, 2005
priority date (Note) -
Abandoned
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Abstract
The agents of the present invention comprise, as a main ingredient, a polyvalent metal inorganic-salt nanocapsule which encapsulates a retinoid such as retinoic acid. The agents could penetrate into a joint when applied to the skin and induce hyaluronic acid production in a synovial membrane or chondrocyte. Moreover, application of the nanocapsule of the present invention to the skin for a certain period of time lowered the values of inflammatory cytokines and MMPs in the blood.
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