Antibodies with Altered Binding to FcRn and Methods of Using Same
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United States of America Patent
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Issued Date -
Apr 7, 2011
app pub date -
Jun 4, 2009
filing date -
Jun 4, 2008
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Abandoned
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Abstract
This invention relates to antibodies with altered binding to FcRn, and particularly antibodies having enhanced binding to FcRn and/or enhanced serum half-lives. The invention also relates to methods of using the antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease.
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