Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders

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United States of America Patent

APP PUB NO 20110076278A1
SERIAL NO

11989362

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods for treatment of ocular disorders using steroids modulate the effects of local and systemic hypoxic events mediated by hypoxia inducible factor-1 (HIF-1). Steroids that are useful as HIF-1 modulators include bufalin, digitoxigenin, digoxin, lanatoside C, strophantin K, uzarigenin, ouabain and proscillaridin. In some embodiments the ocular disorder is characterized by ischmia.

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Patent Owner(s)

Patent OwnerAddress
BIONAUT PHARMACEUTICALS INC16 RUSTIC ROAD STONEHAM MA 02180

International Classification(s)

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  • 2006 Application Filing Year
  • A61K Class
  • 9598 Applications Filed
  • 4848 Patents Issued To-Date
  • 50.52 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2006200720082009201020112012201320142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Khodadoust, Mehran Brookline, US 22 224

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  • 10 Citation Count
  • A61K Class
  • 10.68 % this patent is cited more than
  • 14 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7424023113748323813073422412123001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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