QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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United States of America Patent

SERIAL NO

12766106

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to quinazoline derivatives of formula (1)represents an optionally substituted 5 or 6 membered saturated carbocyclic or heterocyclic group or a group which is alkenyl, alkynyl or optionally substituted alkyl, which alkyl group may contain a heteroatom linking group, which alkenyl, alkynyl or alkyl group may carry a terminal optionally substituted group selected from alkyl and a 5 or 6 membered saturated carbocyclic or heterocyclic group, and salts thereof; processes for their preparation, pharmaceutical compositions containing a compound of formula (I) or a pharmaceutically acceptable salt thereof as active ingredient. The compounds of formula (I) and pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.

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Patent Owner(s)

Patent OwnerAddress
ASTRAZENECA UK LIMITED2 KINGDOM STREET LONDON W2 6BD

International Classification(s)

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  • 2010 Application Filing Year
  • A61K Class
  • 10962 Applications Filed
  • 7633 Patents Issued To-Date
  • 69.64 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2010201120122013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clayton, Edward Cheshire, GB 7 113
Hennequin, Laurent Francois Andre Reims Cedex, FR 75 1381
Johnstone, Craig Cheshire, GB 48 751
Lohmann, Jean-Jacques Marcel Reims Cedex, FR 15 482
Stokes, Elaine Sophie Elizabeth Cheshire, GB 27 395
THOMAS, Andrew Peter Cheshire, GB 56 1114

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Patent Citation Ranking

  • 3 Citation Count
  • A61K Class
  • 10.68 % this patent is cited more than
  • 14 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges7424023113748323813073422412123001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +025050075010001250150017502000225025002750300032503500375040004250

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