PERFLUORO MACROCYCLES IN 18F-LABELLING OF MACROMOLECULES
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United States of America Patent
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Issued Date -
Mar 17, 2011
app pub date -
Aug 28, 2008
filing date -
Aug 29, 2007
priority date (Note) -
Abandoned
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Abstract
The invention relates to a synthetic strategy of using perfluoro crown ethers and other macrocycles to bind to [18F]-labelled fluorination reactions. The optional use of implementing perfluoro kryptofix 2.2.2 in this process is also disclosed. The present invention also claims perfluoro kryptofix structures that are suitable for use in 18F-labelling of fluorous based structures.
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