Methods of reducing excitotoxicity-induced retinal ganglionic neuron degeneration by an orthodenticle HOMOLOG2 (OTX2) homeoprotein

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United States of America Patent

PATENT NO 10722554
APP PUB NO 20110065646A1
SERIAL NO

12812139

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Abstract

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The invention relates to the use of a homeoprotein of the bicoid family, in particular of the Otx family, for enhancing the survival of cultivated retinal ganglion neurones, and for preventing or treating ganglion neuron degeneration particularly occurring in glaucoma.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 RUE MICHEL ANGE 75016 PARIS 75016
ECOLE NORMALE SUPERIEURE45 RUE D'ULM PARIS 75005

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Moya, Kenneth Lee Clichy, FR 3 1
Prochiantz, Alain Paris, FR 21 109

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