USE OF RNA FOR REPROGRAMMING SOMATIC CELLS
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Issued Date -
Mar 17, 2011
app pub date -
Dec 12, 2008
filing date -
Dec 14, 2007
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Abandoned
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Abstract
The present invention provides methods for de-differentiating somatic cells into stem-like cells without generating embryos or fetuses. More specifically, the present invention provides methods for effecting the de-differentiation of somatic cells to cells having stem cell characteristics, in particular pluripotency, by introducing RNA encoding factors inducing the de-differentiation of somatic cells into the somatic cells and culturing the somatic cells allowing the cells to de-differentiate.
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