VV PROMOTER-DRIVEN OVEREXPRESSION OF RECOMBINANT ANTIGENS

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United States of America Patent

SERIAL NO

12680554

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Abstract

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The present invention is directed to the use of a pharmaceutical composition comprising a vaccinia virus (VV) based vector construct under the control of a strong VV specific promoter. The present invention is in particular directed to the use of this pharmaceutical composition for the treatment of infectious diseases, chronic inflammatory or degenerative diseases, and cancer and for evoking an immune response against subdominant and/or cryptic epitopes.

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Patent Owner(s)

Patent OwnerAddress
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH)INGOLSTAEDTER LANDSTRASSE 1 NEUHERBERG 85764

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becker, Pablo Daniel Wolfenbuettel, DE 1 0
Drexler, Ingo Muenchen, DE 2 13
Gasteiger, Georg Muenchen, DE 3 19
Guzmann, Carlos Wolfenbuettel, DE 1 0
Kastenmueller, Wolfgang Muenchen, DE 1 0
Noerder, Miriam Delmenhorst, DE 1 0

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