Methods for Making Simvastatin and Intermediates

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United States of America Patent

SERIAL NO

12763198

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Abstract

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The invention provides synthetic chemical and chemoenzymatic methods of producing simvastatin and various intermediates. In one aspect, enzymes such as hydrolases, e.g., esterases, are used in the methods of the invention.

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Patent Owner(s)

Patent OwnerAddress
VERENIUM CORPORATION4955 DIRECTORS PLACE INTELLECTUAL PROPERTY DEPARTMENT SAN DIEGO CA 92121

International Classification(s)

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  • 2010 Application Filing Year
  • C12P Class
  • 1859 Applications Filed
  • 1029 Patents Issued To-Date
  • 55.36 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201020112012201320142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burk, Mark San Diego, US 26 320
Chaplin, Jennifer San Diego, US 3 1
Greenberg, William San Diego, US 18 127
Huang, Zilin San Leandro, US 13 99
Kustedjo, Karen San Diego, US 7 24
Levin, Michael San Diego, US 157 5138
Morgan, Brian San Diego, US 20 238
Zhu, Zuolin Huaibie, CN 24 74

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges20980520088642120106862401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050100150200250300350400450500550600650700750800850

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