Antibodies specific of the β-amyloid peptides and their uses as diagnostic agents or drugs

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United States of America Patent

PATENT NO 8343493
APP PUB NO 20110059092A1
SERIAL NO

12740217

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Abstract

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A monoclonal antibody which specifically binds to the N-terminal region of Aβ8-x peptide, x being included from 11 to 42, and recognizes neither Aβ1-40 nor Aβ1-42 and which presents a high affinity with respect to Aβ8-x peptide, such as determined by an immunological complex formation between the monoclonal antibody and the peptide Aβ8-x.

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SANOFI46 AVENUE DE LA GRANDE ARMÉE PARIS 75017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blanchard-Bregeon, Veronique Paris, FR 5 29
Buee, Luc Templemars, FR 12 21
Delacourte, Andre Faches Thumesnil, FR 7 129
Gompel, Marie Lille, FR 1 14
Grognet, Pierre Bruxelles Evere, BE 3 94
Pradier, Laurent Verrieres, FR 17 95
Sergeant, Nicolas Ronchin, FR 18 141
VanMechelen, Eugeen Nazareth-Eke, BE 27 605

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