SYNTHESIS OF TIMOSAPONIN BII

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United States of America Patent

APP PUB NO 20110054156A1
SERIAL NO

12990336

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Abstract

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The invention provides a synthetic route from sarsasapogenin to timosaponin BII and related compounds. A diketone intermediate is provided, which can advantageously be used for in situ assembly of complex sugar moieties of the desired glycone end product. The diketone compound is then selectively reduced using a borohydride reducing agent to form the desired end product, certain of the end products and intermediates are novel compounds perse.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE OF RADIATION MEDICINE ACADEMY OF MILITARY MEDICAL SCIENCES PLA100850 NO 27 TAIPING ROAD BEIJING HAIDIAN DISTRICT BEIJING CITY BEIJING CITY 100850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Shuihong Beijing, CN 1 0
Du, Yuguo Beijing, CN 3 1
Li, Lu Beijing, CN 118 612
Ma, Baiping Beijing, CN 5 14
Zhao, Yang Beijing, CN 432 4884

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