ALLERGEN MUTANTS
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United States of America Patent
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app pub date -
Jul 15, 2010
filing date -
May 16, 2002
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Abstract
Novel recombinant allergens with multiple mutations and reduced IgE binding affinity are disclosed. The allergens are mutants of naturally occurring allergens. The overall α-carbon backbone tertiary structure is essentially preserved. Also disclosed is a method for preparing such recombinant allergens as well as uses thereof.
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