Polymerases for Incorporating Modified Nucleotides
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United States of America Patent
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Issued Date -
Feb 24, 2011
app pub date -
Apr 20, 2009
filing date -
Apr 22, 2008
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Abandoned
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Abstract
Compositions and methods are provided that relate to a recombinant protein with DNA polymerase activity in which one or more amino acids are mutated compared with the corresponding wild type protein. The recombinant protein is capable of incorporating one or more modified nucleotides into a nucleic acid substrate with a specific activity greater than 200.
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