AMPLIFICATION OF CANCER-SPECIFIC ONCOLYTIC VIRAL INFECTION BY HISTONE DEACETYLASE INHIBITORS

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United States of America Patent

SERIAL NO

12745030

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Abstract

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The invention provides methods for treating cancer cells in a host by infecting the cancer cells with one or more strains of oncolytic virus, in conjunction with treating the host with an amount of an HDI that is effective to augment the cancer-cell-specific oncolytic infection.

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Patent Owner(s)

Patent OwnerAddress
OTTAWA HOSPITAL RESEARCH INSTITUTEOTTAWA ON K1N 6N5

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abdelbary, Hesham Toronto, CA 1 2
Bell, John Cameron Ottawa, CA 16 22
Diallo, Jean-Simon Ottawa, CA 16 16
Hiscott, John Montreal, CA 5 8
Nguyen, Thi Lien-Anh Montreal, CA 1 2

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