1,3,4-TRISUBSTITUTED BENZENES
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United States of America Patent
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Issued Date -
Feb 17, 2011
app pub date -
Sep 15, 2008
filing date -
Sep 14, 2007
priority date (Note) -
Abandoned
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Abstract
Compounds that are 1,3,4-trisubstituted benzenes which modulate (e.g., inhibit) the activity of γ-secretase. The compounds are expected to reduce the level of Aβ42 in patients and be useful in the treatment of diseases (e.g., Alzheimer's disease) characterized by elevated levels of Aβ42 and/or the formation of Aβ plaques.
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