Imidazopyridinones
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United States of America Patent
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app pub date -
Oct 28, 2010
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Aug 3, 2007
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Abstract
The invention relates to imidazopyridinones, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.By activating TLRs, it should be possible to induce or stimulate immune cells to mount an immune response. In particular, the TLR7 has been implicated in viral infections (such as HCV or HBV), cancers and tumours, and T2 Helper cell (TH2) mediated diseases, and hence TLR7 agonists are potentially useful in the treatment of such diseases.We have now found a series of imidazopyridinones which are agonists of TLR7. According, there is provided a compound of formula (I)alkyl.
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