TRAIL AND METHODS OF MODULATING T CELL ACTIVITY AND ADAPTIVE IMMUNE RESPONSES USING TRAIL

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United States of America Patent

SERIAL NO

12417487

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Abstract

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Methods of modulating a T cell response are provided. Methods include, among other things, contacting a T cell that expresses TNF-related apoptosis-inducing ligand (TRAIL, Apo-2L) or TRAIL receptor (DR4 or DR5) with a molecule that binds to TRAIL (Apo-2L), a molecule that binds to TRAIL receptor (DR4 or DR5), or with a soluble TRAIL (Apo-2L) reagent.

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Patent Owner(s)

Patent OwnerAddress
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY9420 ATHENA CIRCLE SAN DIEGO CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Droin, Nathalie M Memphis, US 2 14
Green, Douglas R Germantown, US 35 396
Janssen, Edith M San Diego, US 2 14
Schoenberger, Stephen P Encinitas, US 6 81

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