PROCESS FOR THE PREPARATION OF (S)- NAPROXEN 4-NITROOXYBUTYL ESTER
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app pub date -
Oct 22, 2010
filing date -
Nov 27, 2001
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Abstract
The present invention relates to a new process for the preparation of the (S)-naproxen 4-nitrooxybutyl ester and to new intermediates obtained and used therein. The invention further relates to the use of the new intermediates for the manufacturing of pharmaceutically active compounds such as (S)-naproxen 4-nitrooxybutyl ester. The invention also relates to the use of (S)-naproxen 4-nitrooxybutyl ester prepared according to the process of the present invention for the manufacturing of a medicament for the treatment of pain.
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