Gastrin Compositions And Formulations, And Methods Of Use And Preparation
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United States of America Patent
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Jul 26, 2010
filing date -
Nov 21, 2002
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Abstract
An embodiment of the invention provided herein is a pharmaceutical composition comprising a gastrin compound having an extended activity upon administration to a subject in comparison with native gastrin. Methods are provided of conjugating portions of the amino acid sequence of gastrin having functional ability to bind to the gastrin/CCK receptor, to various carrier moieties, including the use of amino acid spacer regions, and use of bifunctional cross-linking reagents. Methods of treating a diabetes patient with the compositions are provided.
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