VARIANTS OF THE BACILLUS LICHENIFORMIS ALPHA-AMYLASE
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United States of America Patent
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Issued Date -
Feb 10, 2011
app pub date -
May 28, 2008
filing date -
May 30, 2007
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
alpha-amylase advantageously exhibit improved enzymatic performance. Suitable variants include those with an altered charge distribution on the surface of the enzyme or with altered active site residues. Structural modeling can inform the choice of amino acid modifications so that modified amino acids correspond to residues found in more active alpha amylases, for example. Compositions comprising the variants are useful in methods of cleaning surfaces, laundering textiles, desizing, treating starch, e.g., liquefaction and saccharification, and hydrolyzing biofilms off various substrates.
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International Classification(s)
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- A23L:FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- D06M:TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D0....
- D06L:BLEACHING, e.g. OPTICAL BLEACHING, DRY-CLEANING, O....
- C11D:DETERGENT COMPOSITIONS
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