Lyase Enzymes, Nucleic Acids Encoding Them and Methods for Making and Using Them

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United States of America Patent

APP PUB NO 20110027346A1
SERIAL NO

12303088

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.

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Patent Owner(s)

Patent OwnerAddress
VERENIUM CORPORATION4955 DIRECTORS PLACE INTELLECTUAL PROPERTY DEPARTMENT SAN DIEGO CA 92121

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burke, Ellen San Diego, US 26 320
Healey, Shaun Carlsbad, US 22 299
Podar, Mircea San Diego, US 6 81
Richardson, Toby San Diego, US 48 652
Varvak, Alexander San Diego, US 13 143
Weiner, David Del Mar, US 142 723

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