Method for isolating or identifying a target protein interacting with a lipid in a cell

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United States of America Patent

APP PUB NO 20110020837A1
SERIAL NO

12803886

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is in the field of molecular biology and cell biology. It provides tools and methods for studying the interaction of proteins and lipids in vivo as well as in vitro. The invention relates to a method for isolating or identifying a target protein interacting with a lipid in a cell. This method employs novel dual-labeled lipid precursors such as fatty acids or their derivatives. These lipid precurors comprise two functional groups: a photoactivatable group, such as a diazirine ring, as well as a terminal alkyne or azide moiety.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITEIT UTRECHT HOLDING B VYALELAAN 40 UTRECHT 3584 CM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Haberkant, Per Utrecht, NL 1 10
Sprong, Hendrik Soesterberg, NL 1 10
Van, Meer Gerardus Franciscus Bernardus Petrus Utrecht, NL 1 10

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