IDENTIFYING HAEMATOPOIETIC STEM CELLS BASED ON CELL SURFACE MARKERS
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United States of America Patent
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app pub date -
Mar 19, 2010
filing date -
Oct 30, 2001
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Abstract
The present invention relates to a method of identifying a haematopoietic stem cell (HSC) or progeny thereof comprising the steps of: obtaining a cell sample including HSC or progeny thereof; detecting the presence of at least one carbohydrate sequence having a sequence of at least one disaccharide repeat of glucuronic acid and N-acetylglucosamine or an equivalent thereof; and identifying a HSC or progeny thereof having the sequence or equivalent thereof. The invention also relates to methods of enriching cell populations for HSC or progeny thereof, for isolating HSC or progeny thereof and cell preparations obtained using the methods of their invention and their uses.
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