Method and Kit for Rapid Isolation of Human Foxp3+ Treg Cells
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United States of America Patent
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Issued Date -
Jan 20, 2011
app pub date -
Oct 10, 2008
filing date -
Oct 12, 2007
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Abstract
The present invention relates to methods for isolating human forkhead box P3 (Foxp3+) CD4+ regulatory T cells (herein referred to as Foxp3+ Treg cells) from a sample containing (i) peripheral blood mononuclear cells (PBMCs), (ii) a lymphocyte containing fluid, or (iii) a lymphocyte containing tissue, a kit for isolating human Foxp3+ Treg cells, and the use of anti-CD49d antibody for the isolation of human Foxp3+ Treg cells.
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