MIRNA, SIRNA AND USE THEREOF IN THERAPY
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United States of America Patent
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Issued Date -
Jan 13, 2011
app pub date -
Nov 14, 2008
filing date -
Nov 15, 2007
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Abandoned
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Abstract
The present invention relates to a mixture of molecules comprising at least one miRNA and at least one siRNA, or at least two miRNAs, or at least two siRNAs for inducing hematopoietic differentiation or for treating leukemia wherein the miRNA is able to modulate hematopoietic differentiation and/or to act as oncosuppressor, and the siRNA is able to modulate hematopoietic differentiation or to inhibit the expression of a fusion product deriving from a chromosomic translocation associated to leukemia.
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