SOULUBLE B-N-ACETYLGLUCOSEAMINIDASE BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF
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United States of America Patent
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Issued Date -
Jan 13, 2011
app pub date -
Oct 12, 2007
filing date -
Oct 13, 2006
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Abandoned
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Abstract
The present invention provides compositions comprising an antibiofilm enzyme, a soluble β-N-acetylglucosaminidase similar to the dspB gene (DispersinB™), and an antimicrobial for preventing growth and proliferation of biofilm-embedded microorganisms in acute and chronic wounds, and methods of treatment. The invention further provides methods for preparing medical devices, and in particular, wound care devices using DispersinB™-based antimicrobial compositions.
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