PHARMACEUTICAL COMPOSITIONS FOR TREATING FATTY LIVER DISEASE

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United States of America Patent

APP PUB NO 20110003757A1
SERIAL NO

12865634

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Abstract

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The present invention provides a pharmaceutical composition useful as a therapeutic agent for fatty liver disease. A pharmaceutical composition, which comprises (1S)-1,5-anhydro-1-[5-(azulen-2-ylmethyl)-2-hydroxyphenyl]-D-glucitol or a pharmaceutically acceptable salt thereof, (1S)-1,5-anhydro-1-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-D-glucitol or a pharmaceutically acceptable salt thereof, or alternatively, (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol or a pharmaceutically acceptable salt thereof, more specifically such a pharmaceutical composition for treating fatty liver disease, such as nonalcoholic fatty liver disease in one embodiment, or nonalcoholic simple fatty liver and/or nonalcoholic steatohepatitis in another embodiment.

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INC5-1 NIHONBASHI-HONCHO 2 -CHOME CHUO-KU TOKYO 103-8411 ?103-8411
KOTOBUKI PHARMACEUTICAL CO LTDHANISHINA-GUN NAGANO 389-0697

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kurosaki, Eiji Chuo-ku, JP 6 240
Maeda, Noriaki Chuo-ku, JP 64 759
Takasu, Toshiyuki Chuo-ku, JP 8 83
Yamazaki, Shunji Chuo-ku, JP 3 64

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