System and method for improved processing of nucleic acids for production of sequencable libraries

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United States of America Patent

APP PUB NO 20110003701A1
SERIAL NO

12380139

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An embodiment of an adaptor element for efficient target processing is described that comprises a semi-complementary double stranded nucleic acid adaptor comprising a non-complementary region and a complementary region, where the non-complementary region comprises a first amplification primer site and a second amplification primer site and the complementary region comprises a sequencing primer site and one or more inosine species.

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Patent Owner(s)

Patent OwnerAddress
454 LIFE SCIENCES CORPORATION20 COMMERCIAL STREET BRANFORD CT 06405

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Albert, Thomas J Verona, US 6 243
Braverman, Michael S New Haven, US 4 876
Egholm, Michael Madison, US 64 4043
Ferreri, Gianni Calogero Northford, US 5 69
Godwin, Brian C North Haven, US 4 346
Hutchison, Stephen Kyle Branford, US 3 409
Jeddeloh, Jeffrey Verona, US 11 357
Kitzman, Jacob Seattle, US 8 359
Palmer, Melinda D Hamden, US 1 13
Riches, David Roderick Hamden, US 2 65
Ronan, Michael Todd New York, US 3 287
Simons, Jan F San Francisco, US 7 18

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