CAPILLARY DRIVEN ASSAY DEVICE AND ITS MANUFACTURE
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United States of America Patent
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Issued Date -
Jan 6, 2011
app pub date -
Jul 1, 2010
filing date -
Jul 2, 2009
priority date (Note) -
Abandoned
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Abstract
A method for the manufacture of a capillary driven assay device, includes the steps of: a) providing a capillary substrate, b) modifying the hydrophilicity of the surface of the substrate, c) mixing a matrix and a capturing molecule in a solution to obtain a solution comprising capturing molecules covalently bound to the matrix, and d) depositing the solution in a distinct area in the at least one retaining zone. A capillary driven assay device is obtainable by the method permitting the substrate to be modified with one surface chemistry and capturing molecules to be deposited in an optimal matrix on desired areas. Less matrix material is consumed, permitting several different matrix materials to be used on one chip.
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