Orally Disintegrating Tablet Compositions Comprising Combinations of High and Low-Dose Drugs
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United States of America Patent
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Issued Date -
Dec 30, 2010
app pub date -
May 3, 2010
filing date -
May 1, 2009
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Abstract
The present invention is directed to pharmaceutical compositions comprising a plurality of taste-masked high-dose/low-dose drug-containing microparticles, dosage forms comprising such pharmaceutical compositions (such as an orally disintegrating tablet), and methods of making the pharmaceutical compositions and dosage forms of the present invention. Dosage forms comprising the pharmaceutical compositions of the present invention are improved homogeneous blends of high-dose and low-dose drugs which provide for more convenient and palatable administration of drug combinations, for example for treating pain, hyperglycemia, cardiovascular disease, and allergies.
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