PHAGE-DISPLAYING SINGLE-CHAIN ANTIBODY CAPABLE OF RECOGNIZING NON-REDUCED MANNOSE RESIDUE

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United States of America Patent

APP PUB NO 20100324271A1
SERIAL NO

12300874

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Abstract

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It is an object of the present invention to provide antibodies which recognize non-reducing mannose residues. The present invention provides antibodies recognizing non-reducing mannose residues, which are obtained through screening of phage-display library of human scFvs by using, as an antigen, Man3-DPPE which is an artificial glycolipid synthesized from mannotriose and dipalmitoylphosphatidylethanolamine by reductive amination.

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Patent OwnerAddress
TOKAI UNIVERSITY EDUCATIONAL SYSTEM10-2 TOMIGAYA 2-CHOME SHIBUYA-KU TOKYO 1518677

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chiba, Tomoki Kanagawa, JP 7 6
Kusada, Yu Kanagawa, JP 1 2
Nakata, Munehiro Kanagawa, JP 6 69
Sakai, Keiko Kanagawa, JP 15 89
Shimizu, Nobuyoshi Tokyo, JP 105 1466
Shimizu, Yoshitaka Kanagawa, JP 18 60
Takasaki, Ayano Kanagawa, JP 1 2
Takayanagi, Atsushi Tokyo, JP 52 1087
Yamaguchi, Yoko Kanagawa, JP 41 729

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