SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR COMPOUNDS
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United States of America Patent
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Issued Date -
Dec 16, 2010
app pub date -
Nov 13, 2008
filing date -
Nov 14, 2007
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Abandoned
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Abstract
The invention relates to compounds, in particular 2-amino-3,4,5,-trisubstituted thiophenes, pharmaceutical compositions containing them and the uses of said compounds and compositions for diseases related to sphingosine-1-phosphate (S1P) receptors, predominantly S1P3 receptors. The diseases include cardiovascular diseases, atherosclerosis, cancer, pulmonary oedema, autoimmune disorders and Adult Respiratory Distress Syndrome.
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